What Are The Major And Minor Side Effects Of Rivaroxaban?

Rivaroxaban caused side effects requiring medical attention. Major side effects include bleeding gums, back pain, bladder or bowel dysfunction, blood in the stools, coughing blood, burning sensation, itching, prickling, tingling feeling, dizziness, headache, breathing difficulty, heavy menstrual flow, numbness, leg weakness, paralysis, bleeding continuously from cuts, red urine, vomiting and back pain. Some of the less prominent side effects are wound secretion, leg pain or fainting. Rare side effects like burning sensation and pain while urinating. Incidental side effects are pain in the abdomen, peeling or loose skin, chills, blurred vision, dark urine, cough or hoarseness, diarrhea, fevers, fast heartbeat, loss of appetite, loss of appetite, nausea, vomiting, back pain, swelling in the eyelid, yellow eyes, tiredness, weakness, ulcers and more.

Rivaroxaban causes minor side effects and need medical attention. The body gets accustomed to the medicines and the side effects disappear as time passes. The health care professionals can help reduce the minor side effects. But if the problem persists then it is time to see the doctor immediately. The less side effects include muscle spasm and blisters. Adverse side effects are bleeding complications. The bleeding is increased in patients with severe arterial hypertension and concomitant treatment. Information on the side effects of Xarelto is found at http://sideeffectsofxarelto.org/. Also check http://www.mayoclinic.org/drugs-supplements/rivaroxaban-oral-route/side-effects/drg-20075013 for more details on rivaroxaban oral route side effects.

General reactions lead to anemia due to bleeding. Sometimes bleeding occurs in the critical organ. Sometime the bleeding requires reoperation, low hemoglobin, fatal bleeding, occult blood positive, non-fatal bleeding, thrombocythemia. All this needs transfusion or more than 2 units of whole blood or red blood cells.


The most common adverse reaction in Gastrointestinal patients are diarrhea, constipation, gastrointestinal bleeding, dyspepsia, gastrointestinal hemorrhage, nausea, pain in the teeth, gingival bleeding, vomiting, upper abdominal pain. The uncommon reactions include gastric ulcer, dry mouth, lower abdominal pain, hemorrhage, melena, tongue hemorrhage and in rare cases retroperitoneal bleeding.

Nervous system

The common reaction in the nervous system is headache, dizziness, syncope and uncommon reactions include cerebral hemorrhage and cerebral hemorrhage. The rare incidence of cerebellar hemorrhage, hemorrhagic transformation stroke and fatal intracranial bleeding are seen. Some events not reported include spinal hematoma and intraspinal bleeding.


In the trial cases, stroke was reported in the rivaroxaban transition to warfarin in nonvalvular atrial fibrillation subjects. Common reactions include hematoma, deep vein thrombosis, hypertension, peripheral edema, tachycardia and in rare cases vascular pseudoaneurysm. Incidences not reported include intra articular bleeding and pericardial bleeding, angina pectoris and chest pain.


Common reactions lead to increased transaminases. Uncommon reactions are abnormal hepatic function, increased blood alkaline phosphatase and increased gamma glutamyltransferase. Rare incidences include conjugated bilirubin and jaundice.


The common incidence when it comes to renal includes increased blood urea and creatinine. Uncommon side effects are renal clearance and decreased creatinine. Some frequently not reported incidences include acute renal failure and hypoperfusion. Dermatologic Common incidences include blisters, subcutaneous and cutaneous hemorrhage, contusion, pruritus, ecchymosis, rashes and hemorrhage from the wound and secretions from the wound are seen. Uncommon incidences like allergy, urticaria and dermatitis are seen.


Hyperglycemia, increased LDH, lipase and amylase are uncommon and in rare cases localized edema is seen.